Shire Test Prep


The patient was willing to try LACRISERT® (hydroxypropyl cellulose ophthalmic insert). After being counseled and given a training session by a technician, she began to use LACRISERT once daily in the morning. Since then, the patient had continued to improve.

Four months after she began the LACRISERT therapy, the patient felt that her eyes were doing much better. Her vision improved to 20/60-1 OD and 20/60 OS; superficial punctate keratopathy had decreased to grade 2 in the right eye and grade 2- in the left.

Given the improvement in her symptoms and corneal conditions, a manifest refraction was performed. She received a pair of new glasses, which corrected her vision to 20/50 OD and 20/40-2 OS. She was extremely pleased with her glasses and could now read again.

Paul Karpecki, OD, FAAO
Paul Karpecki, OD, FAAO, works in Corneal Services and is clinical research director at the Koffler Vision Group in Lexington, KY. He is a consultant for Bausch + Lomb and Bio-Tissue Inc.

Indications and Usage

LACRISERT® (hydroxypropyl cellulose ophthalmic insert) is indicated in patients with moderate to severe dry eye syndromes, including keratoconjunctivitis sicca. LACRISERT is indicated especially in patients who remain symptomatic after an adequate trial of therapy with artificial tear solutions. LACRISERT is also indicated for patients with exposure keratitis, decreased corneal sensitivity, and recurrent corneal erosions.

Important Safety Information

  • LACRISERT® (hydroxypropyl cellulose ophthalmic insert) is contraindicated in patients who are hypersensitive to hydroxypropyl cellulose.
  • Instructions for inserting and removing LACRISERT should be carefully followed.
  • If improperly placed, LACRISERT may result in corneal abrasion. Because LACRISERT may cause transient blurred vision, patients should be instructed to exercise caution when driving or operating machinery.
  • The following adverse reactions have been reported, but were in most instances mild and temporary: transient blurring of vision, ocular discomfort or irritation, matting or stickiness of eyelashes, photophobia, hypersensitivity, eyelid edema, and hyperemia.

Please see full Prescribing Information for LACRISERT® (hydroxypropyl cellulose ophthalmic insert).

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